What is helicase?
enzyme that unzips DNA
Helicase is a type of enzyme that plays a key role in DNA replication and repair. Its primary function is to “unzip” the double-stranded DNA molecule by breaking the hydrogen bonds between the complementary base pairs, separating the two strands, and exposing the nucleotide bases. This process is essential to the opening of the replication fork needed for DNA replication. Helicase is also involved in unwinding DNA during transcription, chromosome segregation, and DNA repair. Without the action of helicase, DNA replication cannot occur, which would lead to significant developmental defects or death. Helicases are highly conserved throughout evolution, indicating their fundamental importance to life.
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