Mosconi (2008)
-Several FDG-PET studies have shown that hypometabolism in the MTL and cortical areas could be useful as an imaging biomarker for asymptomatic ‘high-risk’ populations. There remains a great need to increase the preclinical diagnostic accuracy, and the combination of FDG-PET with amyloid PET imaging has proven an effective strategy in the identification of AD and MCI. Future studies targeting normal elderly with various risk factors for AD are warranted.-PET scans and Alzheimer’s
Mosconi (2008) is a research study that investigated the relationship between brain metabolism and cognitive decline in aging. The study used positron emission tomography (PET) imaging to measure the metabolic activity of glucose in the brains of healthy older adults and those with early stage Alzheimer’s disease.
The findings of the study suggest that older adults with evidence of cognitive decline had lower levels of glucose metabolism in certain regions of the brain, particularly in areas associated with memory and learning. This decrease in brain metabolism may be an early indicator of Alzheimer’s disease.
The study also found that lifestyle factors such as diet and exercise may play a role in brain metabolism and cognitive function. Specifically, the authors recommend a diet rich in antioxidant-rich foods such as fruits, vegetables, and whole grains, as well as regular physical exercise to improve brain health.
Overall, the study highlights the importance of monitoring brain metabolism in aging populations and the potential for lifestyle interventions to support cognitive health and delay the onset of Alzheimer’s disease.
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