Understanding DEA Form 222: Proper Procedures for Ordering Schedule I and II Controlled Substances

Who can sign a DEA Form 222?

DEA registrant OR whoever has been granted power of attorney

Only individuals who are authorized to handle controlled substances can sign a DEA Form 222. Specifically, the form can only be signed by the registrant (who must be either a manufacturer, distributor, reverse distributor, or dispenser), or an authorized agent of the registrant. The authorized agent must be specifically named in the registration and must be authorized in writing by the registrant to sign DEA Forms 222 on their behalf. It’s important to note that the DEA Form 222 is used for ordering Schedule I and II controlled substances, which are drugs with a high potential for abuse and a risk of dependence. Proper handling, storage, and ordering of these drugs are crucial to prevent diversion and misuse.

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