How Smallpox Became the First Eradicated Disease: History, Vaccines, and the WHO-led Global Effort

Which human disease has been eliminated due to vaccine?

Smallpox

To date, only one human disease has been eradicated worldwide through the use of vaccines. This disease is smallpox. In 1980, the World Health Organization (WHO) declared that smallpox had been eradicated globally. Smallpox is a viral disease that caused high fever and a characteristic skin rash that left permanent scars on the face and body. Smallpox was a deadly disease, killing up to 30% of those who contracted it. The smallpox vaccine was first introduced in the late 1700s by Edward Jenner, and over the next two centuries, vaccination campaigns helped to reduce the incidence of smallpox around the world. A coordinated, global effort led by the WHO in the 1960s and 1970s, including vaccination and surveillance measures, ultimately led to the complete eradication of smallpox.

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