Propylthiouracil may be used to treat hyperthyroidism, because ita. destroys thyroid gland cells.b. inhibits the release of TSH.c. suppresses production of autoantibodies.d. inhibits thyroid hormone synthesis.
The correct answer is d
The correct answer is d. inhibits thyroid hormone synthesis.
Propylthiouracil (PTU) is a medication commonly used to treat hyperthyroidism, a condition characterized by an overactive thyroid gland that produces excessive amounts of thyroid hormones. PTU works by inhibiting the synthesis of thyroid hormones in the thyroid gland.
The thyroid gland produces two main hormones: thyroxine (T4) and triiodothyronine (T3). These hormones play a crucial role in regulating the body’s metabolism, growth, and development. In hyperthyroidism, the thyroid gland becomes overactive, leading to excessive production of T4 and T3.
PTU acts as a thioureylene drug that interferes with the normal production of thyroid hormones. It inhibits an enzyme called thyroid peroxidase, which is responsible for the production of thyroid hormones. By inhibiting this enzyme, PTU reduces the conversion of the amino acid tyrosine into the thyroid hormones T4 and T3.
By decreasing the synthesis of thyroid hormones, PTU helps to lower the levels of circulating T4 and T3, effectively slowing down the overactive thyroid gland. This helps to alleviate the symptoms of hyperthyroidism and restore the balance of thyroid hormone levels in the body.
It is important to note that PTU does not destroy thyroid gland cells (a). Instead, it temporarily reduces their hormone-producing capacity. PTU also does not directly inhibit the release of TSH (thyroid-stimulating hormone) (b), which is produced by the pituitary gland to stimulate the thyroid gland. However, by reducing the levels of thyroid hormones, PTU indirectly decreases the stimulation of TSH production. Additionally, PTU does not suppress the production of autoantibodies (c), which are antibodies that mistakenly attack the thyroid gland in autoimmune thyroid diseases such as Graves’ disease.
In summary, PTU is an effective treatment for hyperthyroidism because it inhibits the synthesis of thyroid hormones in the thyroid gland, thereby reducing their levels in the body and helping to normalize thyroid function.
More Answers:
Understanding Goiter: Causes, Symptoms, and TreatmentThe Role of Angiotensin II in Regulating Aldosterone Secretion: A Key Component of the Renin-Angiotensin-Aldosterone System
Understanding Myxedema Coma: Causes, Symptoms, and Treatment for Severe Hypothyroidism