Precautions for Administering Piperacillin/Tazobactam: Importance of Inquiring About Penicillin Allergies

A nurse is preparing to administer the first dose of piperacillin/tazobactam to a patient in an infusion clinic. The nurse should take which of the following precautions?A. Ask the patient about past allergic reactions to penicillins. B. Ask the patient about past allergic reactions to aminoglycosides.C. Mix the piperacillin/tazobactam with lidocaine to reduce pain of infusion. D. Instruct the patient to eat a snack to decrease stomach upset from piperacillin/tazobactam.

A

A. Ask the patient about past allergic reactions to penicillins.

The first necessary precaution that the nurse should take before administering the first dose of piperacillin/tazobactam is to ask the patient if he/she has any history of allergic reactions to penicillins. This is because piperacillin/tazobactam is a penicillin antibiotic and can cause severe allergic reactions in patients who have had allergy to penicillins before.

Option B is not necessary as aminoglycosides are not related to piperacillin/tazobactam.

Option C is incorrect, and the nurse should never mix piperacillin/tazobactam with any medication without proper instructions from the pharmacist or prescriber.

Option D is also incorrect as there is no need for the patient to eat a snack to decrease stomach upset from piperacillin/tazobactam. Drinking additional water or taking antacids may help with stomach upset.

Therefore, option A is the correct precaution that the nurse should take before administering the first dose of piperacillin/tazobactam.

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