What hemoglobin consists of four gamma chains?
Hemoglobin Bart’s
Hemoglobin is a complex protein molecule found in red blood cells that is responsible for carrying oxygen to different parts of the body. It is made up of four subunits, known as globins, each of which is further composed of a heme group and a polypeptide chain. The exact composition of these globins can vary depending on the organism, with humans typically having two alpha globin chains and two beta globin chains.
However, in certain situations, such as during fetal development or in individuals with certain genetic disorders, hemoglobin may instead consist of four gamma chains. These chains are similar in structure to the alpha and beta chains of hemoglobin, but differ in their amino acid sequence. The presence of gamma chains in hemoglobin alters the molecule’s oxygen-binding affinity and can affect its ability to transport oxygen in the body.
Overall, the composition of hemoglobin is crucial for its normal functioning, and any alterations in its structure or subunit composition can result in a range of medical conditions.
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