Sickle Cell Trait: Prevalence and Ethnicity Implications

Which percentage of American blacks carry the trait (one gene) for hemoglobin S?

8-10%

According to the Centers for Disease Control and Prevention (CDC), approximately 1 in 13 African American babies is born with sickle cell trait (SCT), which is also known as carrying one gene for hemoglobin S. This means that approximately 7.7% of African Americans carry the trait. SCT is more common among certain ethnic groups, including African Americans, people of Hispanic origin, and people of Middle Eastern, Asian, Indian, and Mediterranean descent.

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