Pathology | Senioritis

Mohamed Abbas
July 4, 2023
Pathology

The Multifunctional Role of the Endoplasmic Reticulum in Cellular Function and Physiology

A system of membranes where lipids are synthesized, calcium levels are regulated, and toxic substances are broken down. The system we are referring to is the endoplasmic...

Mohamed Abbas
July 4, 2023
Pathology

The Endoplasmic Reticulum: A Key Player in Protein Synthesis, Lipid Metabolism, and Calcium Regulation in Cells

System of internal membranes within the cytoplasm. Membranes are rough due to the presence of ribosomes. functions in transport of substances such as proteins within the cytoplasm...

Mohamed Abbas
July 4, 2023
Pathology

Centrioles: The Key Players in Cell Division and the Mitotic Spindle Assembly

Cell organelle that aids in cell division (part of the cytoskeleton) The organelle that aids in cell division and is part of the cytoskeleton is the centriole...

Mohamed Abbas
July 4, 2023
Pathology

Unveiling the Role of Lysosomes: The Powerhouses of Intracellular Digestion and Cellular Recycling

An organelle containing digestive enzymes The organelle that contains digestive enzymes is called the lysosome The organelle that contains digestive enzymes is called the lysosome. Lysosomes are...

Mohamed Abbas
July 4, 2023
Pathology

Understanding the Difference Between Liquid Tumors and Solid Tumors in Cancer: A Comprehensive Guide

Liquid tumor; Leukemia: bone marrow; Lyphoma: lymph nodes & tissueSolid tumor: bones & soft tissue A liquid tumor refers to a type of cancer that primarily affects...

Mohamed Abbas
July 4, 2023
Pathology

Detecting the EWS/FLI1 Fusion Transcript in Ewing’s Cancer: A Guide to using Reverse-Transcriptase PCR (RT-PCR) with Targeted Primers

EWS/ EWINGScancer/solid tumort(11:22)Reverse-Transcriptase PCR (RT-PCR)PCR primers designed to yield product only if translocation has occurred In the case of Ewing’s cancer, also known as Ewing’s sarcoma, a...

Mohamed Abbas
July 4, 2023
Pathology

Understanding Abnormal Lymphoblast Production in Bone Marrow

ALLt(9:22)FISH, CISH, RTPCRFound in the bone marrowhigh lymphoblast production leaves little or no normal cell production/population It seems you have provided some information about a specific condition...

Mohamed Abbas
July 4, 2023
Pathology

How Translocation Events Impact Gene Expression: Loss of Function in DNA Binding Proteins

PMLt(15:17)FISH, RTPCRRARA (15) + PML (17) genes both are DNA Binding proteinsWhen translocation = loss of function for both and affects gene expression due to lack of...