Pathology | Senioritis

Mohamed Abbas
July 4, 2023
Pathology

Unraveling the Genetic Traits of Cancer Cells: From Growth Factor Independence to Metastasis

1. Does not need growth factors (i.e. as long as RAS protein is activated)2. Loss of anchorage-dependence inhibition3. Unregulated division (i.e. mutation of cancer-critical genes)4. Telomere reactivation5....

Mohamed Abbas
July 4, 2023
Pathology

The Role of Mitogens and Growth Factors in Cell Division: Influential Signals for Regulating Cellular Proliferation

○ influences cell division○ stimulate other cells to grow and divide When it comes to cell division, there are various factors that influence this process When it...

Mohamed Abbas
July 4, 2023
Pathology

Understanding Contact Inhibition: A Mechanism for Cell Growth Regulation and Tissue Homeostasis

crowded cells stop dividing When cells become crowded, they can stop dividing due to a phenomenon known as contact inhibition When cells become crowded, they can stop...

Mohamed Abbas
July 4, 2023
Pathology

The Role of Surface Attachment in Cell Division: Importance, Signaling, and Contact Inhibition

cells must be attached to a surface for division; once a layer is built, cells stop dividing In the context of cell division, cells generally require a...

Mohamed Abbas
July 4, 2023
Pathology

Unraveling the Complex Process of Carcinogenesis: From Normal Cell to Cancer Cell Transformation

○ process where normal cell turns into a cancer cell○ occurs when genes regulating cell growth & division mutates (cancer-critical genes) The process by which a normal...

Mohamed Abbas
July 4, 2023
Pathology

Unraveling the Role of Proto-Oncogenes and Tumor-Suppressor Genes in Cancer Development: Insights into Mutations and Implications for Targeted Therapies

genes whose mutations contribute to cancere.g. proto-oncogenes & tumor-suppressor genes In order to understand the genes whose mutations contribute to cancer, it is important to first understand...

Mohamed Abbas
July 4, 2023
Pathology

Genes that Promote Cell Growth and Division: An In-depth Look at Key Players and their Functions

genes that promote growth and division of normal cells There are several genes that play a crucial role in promoting growth and division of normal cells There...

Mohamed Abbas
July 4, 2023
Pathology

The Role of Mutated Proto-Oncogenes in Cancer Development and Progression: Insights for Targeted Therapies

mutated form of proto-oncogenes Proto-oncogenes are normal genes that help regulate cell growth and division Proto-oncogenes are normal genes that help regulate cell growth and division. They...