Science | Senioritis

Mohamed Abbas
July 4, 2023
Biotechnology

Optimizing the Inhaler Design and Engineering Process for Large Quantities of Exubera: Ensuring Physical Integrity, Aerosolization, and Dosage Precision

Extensive Design and engineering for large quantity with consistent quality, must reach site of action physically and structurally intact. Ex. Unstable in Oral route, administered in parenteral...

Mohamed Abbas
July 4, 2023
Biotechnology

Unlocking the Potential of Antisense Technology: Precision Gene Expression Inhibition for Targeted Therapy

Antisense Technology, block DNA transcription or RNA translation Antisense technology is a molecular biology technique that involves using synthetic nucleic acids called antisense oligonucleotides (ASOs) to block...

Mohamed Abbas
July 4, 2023
Biotechnology

The Importance of Specificity, Broad Applicability, Rational Design, Efficiency, and Manufacturing in Scientific Research: A Comprehensive Overview

Specificity, Broad Applicability, Rational Design, Efficiency, Manufacturing (Low Cost) Specificity refers to the ability of a scientific method or approach to accurately target or identify a specific...

Mohamed Abbas
July 4, 2023
Biotechnology

Optimizing Oligonucleotide-Based Therapies: Addressing Stability and Bioavailability Challenges in Medicine

Mechanism of Action, Medicinal Chemistry of Oligonucleotides (Metabolism, Affinity, Synthesis), Toxicology, -BIGGEST PROBLEM – Less Stable in body, low bioavailability Oligonucleotides are short sequences of nucleotides (building...

Mohamed Abbas
July 4, 2023
Biotechnology

Blocking Activation Site of Translation and Degradation by RNAse: Mechanisms to Inhibit Protein Synthesis in Science

1. Blocking activation site of translation.2. Degraded by an enzyme RNAse One way to block the activation site is by using molecules called antisense oligonucleotides 1. Blocking...

Mohamed Abbas
July 4, 2023
Biotechnology

Advancements in Medication: Vitravene, KYNAMRO, Custirsen, ISIS GCGR, and Alicaforsen

Vitravene – Fomivirsen (marketed)KYNAMRO (approved)Custirsen (cancer drug, Phase III)ISIS GCGR (Phase II)Alicaforsen (approved) Vitravene, also known as Fomivirsen, is a medication that was previously marketed for the...

Mohamed Abbas
July 4, 2023
Life Science

Achieving and Sustaining Balance: Key Aspects of Balancing Human and Living Organisms

balancing human or any living organisms Balancing human or any living organisms refers to maintaining a state of equilibrium in various aspects of their existence, including physical...

Mohamed Abbas
July 4, 2023
Life Science

Unlocking the Secrets of Metabolism: Exploring the Chemical Processes within Living Cells

the chemical process occurring within a living cell or organism that are necessary for the maintenance of life The chemical processes occurring within a living cell or...