Science | Senioritis

Mohamed Abbas
July 4, 2023
Pathology

Exploring the Role of CCND1 Overexpression in Mantle Cell Lymphoma: A Molecular Perspective for Targeted Therapies

MCLt(11:14)FISH, PCR, RTPCRMutations increase expression of CCND1 forcing cells from G1 to S phase. Affects B cells and develops in the mantle zone in the lymph node....

Mohamed Abbas
July 4, 2023
Pathology

Unlocking the Potential: The Significance of the c-myc Gene in Gene Regulation and Cancer Development

BLt(8:14)FISH, CISHc-myc gene codes for transcription factor that controls transcription of other genes The c-myc gene is an important gene that codes for a transcription factor The...

Mohamed Abbas
July 4, 2023
Pathology

A Step-by-Step Guide to Designing Primers for Translocation-Specific PCR: Understanding, Gene Sequences, Breakpoints, Designing Criteria, Validation

RMS/ARMScancer/solid tumort(2:13) or t(1:13)RTPCR, FISHPCR primers designed to yield product only if translocation has occurred To design primers for a translocation-specific PCR (Polymerase Chain Reaction), such as...

Mohamed Abbas
July 4, 2023
Pathology

Unraveling the Genetic Landscape of Breast Cancer: Insights from Chromosome 17 and Molecular Techniques.

Breast cancerChromosome 17IHC (Immunohistochemistry), FISH, CISHTyrosine phosphatase (adds phosphates to tyrosines)25-30% of all breast cancersHerceptin is the main drug since it’s a tyrosine kinase inhibitor Breast cancer...

Mohamed Abbas
July 4, 2023
Immunology

The Science Behind Reflexes: Sneezing, Coughing, Vomiting, and Diarrhea as Involuntary and Protective Responses

reflexes (sneezing, coughing, vomiting, and diarrhea) Reflexes are involuntary, rapid, and automatic responses to specific stimuli Reflexes are involuntary, rapid, and automatic responses to specific stimuli. They...

Mohamed Abbas
July 4, 2023
Immunology

The Importance of Skin and Mucous Membranes in the Body’s Defense System: Roles, Functions, and Protection from Infections

skin and mucous membranes Skin and mucous membranes are two important components of the body’s defense system, acting as barriers against harmful microorganisms and foreign particles Skin...

Mohamed Abbas
July 4, 2023
Immunology

The Crucial Role of Phagocytosis in the Immune System: Understanding and Manipulating for Therapeutic Purposes

performs phagocytosis Phagocytosis is a process by which cells engulf and digest foreign particles, debris, or pathogens Phagocytosis is a process by which cells engulf and digest...

Mohamed Abbas
July 4, 2023
Anatomy

Understanding the Significance of Fasci/o: Exploring the Anatomical and Surgical Applications of Fibrous Connective Tissue

fasci/o “Fasci/o” is a combining form used in medical terminology, specifically in the fields of anatomy and surgery “Fasci/o” is a combining form used in medical terminology,...