OsO4 adds?
loss of CO2 (i.e. decarboxylation)
OsO4 (osmium tetroxide) adds via syn dihydroxylation reaction. This means that OsO4 adds two hydroxyl groups (-OH) to the double bond of an alkene, forming a vicinal diol. The reaction occurs in the presence of a suitable solvent such as acetone or tetrahydrofuran (THF) and usually requires the use of a co-oxidant like NMO (N-methylmorpholine N-oxide). This reaction is highly stereospecific and yields a cis-diol product. The mechanism of OsO4 addition involves the formation of a cyclic osmate ester intermediate, which subsequently undergoes hydrolysis to yield the diol product.
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