At what speed does DNA polymerase replicate? (i.e. How many nucleotides per second?)
1000 nucleotides per second
The speed at which DNA polymerase replicates DNA can vary depending on several factors and conditions, including the type of organism, the location of the replication fork, and the presence of any obstacles or errors in the replication process.
In general, the rate of DNA synthesis by DNA polymerase is estimated to be around 1000 nucleotides per second in bacteria. However, in eukaryotic cells, this rate can vary widely from 10 to 100 nucleotides per second, depending on the specific polymerase used, the properties of the DNA template, and the availability of nucleotides and other cofactors.
It is important to note that this rate is not constant throughout the replication process and can be influenced by several factors, including interactions with other replication proteins, DNA damage and repair mechanisms, and the availability of nucleotides and other cofactors.
Overall, while there is no single answer to the question of how many nucleotides per second DNA polymerase can replicate, the rate can be influenced by a variety of factors, and researchers are still working to fully understand the underlying mechanisms and dynamics of DNA replication.
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