WBC Casts in Urine: Indicators of Kidney Inflammation and Possible Underlying Conditions

WBC casts in urine indicate

Infection (UTI and pyelonephritis). WBC casts and proteinuria are associated with upper tract infection, pyelonephritis (rather than simple cystitis)

The presence of WBC casts in urine is indicative of inflammation or an immune response in the kidneys. White blood cell casts are formed when white blood cells (WBCs) cluster and adhere to cylindrical structures called tubular casts that are typically found in the kidneys.

This may be caused by a number of different conditions including urinary tract infections, pyelonephritis (infection of the kidneys), glomerulonephritis (inflammation of the kidney’s filtering system), and interstitial nephritis (inflammation of the kidney tissue).

The presence of WBC casts in urine is generally considered an abnormal finding, and further evaluation is necessary to determine the underlying cause of the inflammation. A urinalysis is usually the first step in diagnosing the cause of WBC casts, although additional tests may be required such as a urine culture or blood test.

Prompt medical attention is necessary if you are experiencing any symptoms such as painful or frequent urination, lower back pain, fever, or blood in the urine. Your healthcare provider can provide treatment specific to the underlying cause and help prevent any potential complications.

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