Progesterone and Progestins: Natural vs. Synthetic Hormones in Hormonal Contraceptives and Hormone Replacement Therapy

the major progestin found circulating is progesterone; this is the only group that has one hormone in it

progestins

Progesterone is a steroid hormone synthesized in the ovaries, placenta, and adrenal glands. It is considered the primary progestin hormone found circulating in the human body. However, it is important to note that progestins are a class of synthetic hormones that includes progesterone and other compounds designed to mimic its effects.

Progestins have been used in hormonal contraceptives and hormone replacement therapy, as they are able to prevent ovulation and thicken cervical mucus, among other effects. Some progestins used in these therapies include levonorgestrel, norethindrone, and medroxyprogesterone acetate.

Therefore, while progesterone may be the most prevalent and natural progestin found in the human body, there are other synthetic progestins that have important medical uses.

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