Epinephrine Dose/Route (anaphylaxis)
0.3 mg IM 1:1000Peds: 0.01mg/kg 1:1000 IM/SQ max of 3mg
Epinephrine is a life-saving medication used to treat anaphylaxis, a severe allergic reaction that can cause swelling, difficulty in breathing, low blood pressure, and other life-threatening symptoms. The recommended dose and route of epinephrine for anaphylaxis are as follows:
Adults:
– Intramuscular (IM) injection of 0.3-0.5 mg of 1:1000 epinephrine into the lateral thigh muscle.
– Repeat dose every 5-15 minutes as needed, up to a maximum of three doses.
– In severe cases, the dose may be increased to 1 mg and administered at shorter intervals under medical supervision.
Children:
– The dose of epinephrine for children varies based on their weight.
– For children weighing less than 30 kg (66 lbs), the recommended dose is 0.01 mg/kg of 1:1000 epinephrine, with a maximum dose of 0.3 mg.
– For children weighing more than 30 kg (66 lbs), the recommended adult dose of 0.3-0.5 mg may be used.
– Intramuscular (IM) injection into the lateral thigh muscle is the preferred route of administration for children, as it provides better absorption and faster onset of action.
– Repeat doses may be given every 5-15 minutes, up to a maximum of three doses.
It is important to remember that epinephrine should only be administered in cases of severe anaphylaxis under the supervision of a medical professional. If you or someone you know is experiencing symptoms of anaphylaxis, call 911 or seek emergency medical attention immediately.
More Answers:
Diphenhydramine: Uses, Benefits, and Available Forms of the Antihistamine DrugSide Effects of Epinephrine in Treating Anaphylaxis
Epinephrine: Onset and Duration of Action for Medical Conditions including Anaphylaxis