T-cell receptors
bind antigens or specific peptides presented by antigen presenting cells
T-cell receptors (TCRs) are proteins that are found on the surface of T cells, a type of white blood cell that is part of the adaptive immune system. The primary function of TCRs is to recognize and bind to specific antigens, which are protein fragments or peptides that are presented on the surface of infected or cancerous cells.
TCRs have two main protein chains, called alpha and beta chains, that are joined together and form a binding site that can recognize antigens. The binding site has a shape that matches a specific antigen peptide, allowing the TCR to bind to it with high specificity. TCRs also have a variable region that is highly diverse, allowing the immune system to recognize a wide range of antigens.
Once the TCR binds to an antigen, it triggers a signal inside the T cell that activates the immune response. This can include the release of cytokines, recruitment of other immune cells, and the proliferation and differentiation of the T cells themselves.
TCRs play a central role in the adaptive immune response and are key to the ability of the immune system to recognize and respond to a wide range of pathogens and abnormal cells.
More Answers:
Understanding Herd Immunity and Its Importance in Public Health.The Science of Immunity: Understanding the Innate and Adaptive Immune System and How to Boost Your Body’s Defenses.
Understanding the Role of B Cells in Adaptive Immunity and Disease