The Importance of IgM in Immune Response and Pathogen Defense: A Comprehensive Overview

Immunoglobulins, formed of five subunits, that are the first antibodies to be produced in response to infection, areA) IgA.B) IgD.C) IgE.D) IgG.E) IgM.

The correct answer is E) IgM

The correct answer is E) IgM.

IgM, or immunoglobulin M, is the first antibody to be produced in response to an infection. It is classified as a pentameric antibody, meaning it consists of five subunits. Each subunit is composed of two heavy chains and two light chains, making a total of ten chains in the IgM molecule. IgM is also the largest antibody in the body.

The production of IgM is initiated when the immune system detects foreign substances, such as pathogens or antigens. B cells, a type of white blood cell, are activated and start to differentiate into plasma cells. Plasma cells are responsible for secreting antibodies, including IgM.

IgM plays a critical role in the early stages of the immune response. It helps to neutralize and eliminate pathogens by binding to their antigens, preventing them from infecting host cells. Additionally, IgM can activate other components of the immune system, such as complement proteins, to further enhance the elimination of pathogens.

While IgM is the first antibody to be produced in response to an infection, other types of antibodies like IgG, IgA, IgE, and IgD are also produced later in the immune response. Each antibody type has unique functions and roles in the immune system’s defense against pathogens.

More Answers:

The Role of Interferons in Initiating Signaling and Activating the Antiviral State Against Viral Infections
Sentinel Cells: Key Players in Immune Response to Viral Infections – The Role of Type I Interferons
The Primary Activation of B Cells by Antigens and the Production of Antibodies: A Comprehensive Overview

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