If the disulfide bonds in IgG were broken, how many peptide chains would be set free? A) 2B) 4C) 6D) 8E) 1
If the disulfide bonds in IgG were broken, each IgG molecule is composed of two identical heavy chains and two identical light chains
If the disulfide bonds in IgG were broken, each IgG molecule is composed of two identical heavy chains and two identical light chains. The disulfide bonds link these chains together and contribute to the stability and structure of the immunoglobulin.
Each disulfide bond connects two cysteine amino acid residues in the different chains, resulting in the formation of a covalent bond between the sulfur atoms of the cysteines. To break the disulfide bond, an oxidizing agent or reducing agent is applied, which causes the sulfur atoms to separate and form two separate thiol groups (-SH) in the cysteines.
Since an IgG molecule has a total of 2 heavy chains and 2 light chains, the breaking of one disulfide bond will release two peptide chains, comprising one light chain and one heavy chain.
Therefore, if the disulfide bonds in IgG were broken, the correct answer would be A) 2, as two peptide chains would be set free.
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