Short Half-Life of Cytokines for Precise Signaling Control

T/F: most cytokines are rapidly synthesized and have a long half-life

F: they have short half-lives so that we don’t have a build up of cytokines in our bodies (eg. cytokine storms)

False. Most cytokines are rapidly synthesized, but they have a short half-life, ranging from minutes to hours. This is because they are rapidly degraded in order to maintain precise control of their signaling effects.

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