Holocrine Glands
Cells rupture and spill the entire cell contents into the duct. Sebaceous Glands (Oil Glands)
Holocrine glands are a type of exocrine gland that releases its secretion by the complete disintegration of its entire secretory cells. Unlike merocrine and apocrine glands, which release their secretions through the exocytosis of secretory vesicles or the budding off of apical portions of cells, respectively, holocrine glands release their products by releasing whole cells.
Examples of holocrine glands include sebaceous glands, which are found in the skin and produce an oily substance called sebum that lubricates and protects the skin and hair. Sebum is composed of a complex mixture of lipids, including triglycerides, wax esters, squalene, and cholesterol.
Holocrine glands have a slower rate of secretion compared to merocrine and apocrine glands. However, they have the advantage of producing a more viscous and concentrated secretion due to the incorporation of cellular debris and lipids.
While holocrine glands are important for maintaining healthy skin and hair, they can also be responsible for skin and hair problems such as acne and oily hair. Understanding their function and regulation is important in the development of treatments for these conditions.
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