Hematology | Senioritis

Mohamed Abbas
June 21, 2023
Hematology

Unveiling Ferroportin Protein’s Crucial Role in Iron Metabolism and Treatments for Related Disorders

Ferroportin Transports iron into the blood across the basolateral membrane Ferroportin is a protein that plays a crucial role in the transportation of iron out of cells....

Mohamed Abbas
June 21, 2023
Hematology

Filgrastim: The Importance of G-CSF in Treating Neutropenia and Other Blood Disorders

G-CSF (filgrastim) Binds to a JAK/STAT receptor, stimulates proliferation and differentiation of progenitors already committed to the neutrophil lineage G-CSF (granulocyte-colony stimulating factor) is a medication that...

Mohamed Abbas
June 21, 2023
Hematology

Benefits and Risks of Sargramostim: A Key Drug for Supporting Immune Function

GM-CSF (sargramostim) Binds to a JAK/STAT receptor, multipotential hematopoietic growth factor that stimulates proliferation and differentiation of early and late granulocytic progenitor cells as well as erythroid...

Mohamed Abbas
June 21, 2023
Hematology

Hemochromatosis: Causes, Symptoms, and Treatment Options for Iron Overload Disorder

Hemochromatosis Excess iron is deposited in the heart, liver, pancreas, and other organs, can lead to organ failure and death, most common in patients with inherited excessive...

Mohamed Abbas
June 21, 2023
Hematology

Effective Treatment for Blood Disorders: Hydroxyurea for Sickle Cell Anemia, Polycythemia Vera, Chronic Myeloid Leukemia, and Essential Thrombocythemia

Hydroxyurea Cancer chemotherapeutic drug used to treat sickle cell disease, acts through poorly defined pathways to increase the production of fetal hemoglobin γ (HbF), which interferes with...

Mohamed Abbas
June 21, 2023
Hematology

Interleukin-11 (IL-11): Functions, Signaling Pathways, and Clinical Applications of Oprelvekin.

Interleukin-11 (Oprelvekin) Stimulates the growth of multiple lymphoid and myeloid cells including primitive megakaryocytic progenitors, increases the number of peripheral platelets and neutrophils, approved for thrombocytopenia in...

Mohamed Abbas
June 21, 2023
Hematology

The Role of Romiplostim for Optimizing Platelet Counts in Chronic Immune Thrombocytopenia (ITP) Treatment

Romiplostim Novel biologic agent that activates the thrombopoietin receptor, approved for idiopathic thrombocytopenic purpura Romiplostim is a type of medication used to treat low platelet count in...

Mohamed Abbas
June 21, 2023
Hematology

Discovering the Cause of Vitamin B12 Malabsorption: Schilling Test

Schilling test Measures absorption and urinary excretion of radioactive vitamin B12 The Schilling test is a diagnostic test used to determine the cause of vitamin B12 malabsorption....