removes damaged, abnormal, RBCs from circulation
hemolysis
The process of removing damaged, abnormal, or old red blood cells (RBCs) from the circulation is called erythrophagocytosis. This process is carried out by specialized cells in the body called macrophages. Macrophages are large, immune cells that exist in various tissues throughout the body and are involved in a range of different functions, including phagocytosis.
In the case of erythrophagocytosis, macrophages in the spleen, liver, and bone marrow play a crucial role in clearing out old and damaged RBCs from circulation. These macrophages recognize and engulf the damaged RBCs, break them down into small particles, and recycle the components of the RBCs that can be used to make new RBCs.
The removal of damaged RBCs from circulation is important for maintaining the health and function of the body. If too many damaged RBCs accumulate in the circulation, they can lead to a variety of health problems, including anemia, jaundice, and organ damage.
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