Understanding DNA Base Pairing: Determining the 30% Guanine Content in a DNA Sample

A sample of DNA contains 20% adenine. What percentage of guanine does it contain?

To determine the percentage of guanine (G) in the DNA sample, we need to know that DNA has a complementary base pairing structure

To determine the percentage of guanine (G) in the DNA sample, we need to know that DNA has a complementary base pairing structure. In DNA, adenine (A) pairs with thymine (T), and guanine (G) pairs with cytosine (C). The number of adenine bases in a DNA sample will be equal to the number of thymine bases, and similarly, the number of guanine bases will be equal to the number of cytosine bases.

Since we know that the DNA sample contains 20% adenine (A), we can infer that the sample will also contain 20% thymine (T) because they pair in equal amounts.

This means that the remaining bases, guanine (G) and cytosine (C), must each make up 30% (100% – 20% – 20%).

Therefore, the percentage of guanine (G) in the DNA sample is 30%.

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