Iodide: Importance in Thyroid Hormone Synthesis, Metabolism and Medical Applications

Iodide

I⁻

Iodide is an anion that is formed from the chemical element iodine. It has a negative charge and is represented by the symbol I^-. Iodide is commonly found in many minerals and salts, including sodium iodide and potassium iodide.

In the human body, iodide is important for the synthesis of thyroid hormones, which are essential for proper growth and development. The thyroid gland absorbs iodide from the bloodstream and uses it to produce the hormones thyroxine (T4) and triiodothyronine (T3). These hormones play a key role in regulating metabolism, energy production, and maintaining healthy skin, hair, and nails.

Iodide is also used for medical diagnostic purposes, particularly in the imaging of the thyroid gland. Radioactive iodine isotopes are taken up by the thyroid gland, allowing for visualization and diagnosis of any abnormalities.

In addition, iodide can be used in the treatment of certain medical conditions such as thyroid cancer, goiter, and hyperthyroidism. It can also be used as an antioxidant and in the preparation of organic compounds.

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