The Efficiency of Co-Translational Translocation: Ribosomes’ Location on the Surface of the Endoplasmic Reticulum (ER)

Why is the location of ribosomes on the surface of the endoplasmic reticulum efficient?

to help move proteins throughout the cell

The location of ribosomes on the surface of the endoplasmic reticulum (ER) is efficient because it allows for the direct transfer of newly synthesized proteins into the lumen of the ER for further modification and processing. The ribosomes on the surface of the ER are attached to the membrane by their ribosomal subunits, allowing the newly synthesized proteins to be translocated across the ER membrane and into the ER lumen. This process is known as co-translational translocation, and it enables efficient processing and modification of proteins as they are being synthesized. Additionally, the close proximity of the ribosomes and the ER membrane allows for efficient transfer of lipids and other molecules between the two compartments, further enhancing cellular efficiency.

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