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  • Mohamed Abbas
  • July 4, 2023
  • Biotechnology

Optimizing Oligonucleotide-Based Therapies: Addressing Stability and Bioavailability Challenges in Medicine

Mechanism of Action, Medicinal Chemistry of Oligonucleotides (Metabolism, Affinity, Synthesis), Toxicology, -BIGGEST PROBLEM – Less Stable in body, low bioavailability Oligonucleotides are short sequences of nucleotides (building...
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  • Mohamed Abbas
  • July 4, 2023
  • Biotechnology

Blocking Activation Site of Translation and Degradation by RNAse: Mechanisms to Inhibit Protein Synthesis in Science

1. Blocking activation site of translation.2. Degraded by an enzyme RNAse One way to block the activation site is by using molecules called antisense oligonucleotides 1. Blocking...
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  • Mohamed Abbas
  • July 4, 2023
  • Biotechnology

Advancements in Medication: Vitravene, KYNAMRO, Custirsen, ISIS GCGR, and Alicaforsen

Vitravene – Fomivirsen (marketed)KYNAMRO (approved)Custirsen (cancer drug, Phase III)ISIS GCGR (Phase II)Alicaforsen (approved) Vitravene, also known as Fomivirsen, is a medication that was previously marketed for the...
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  • Mohamed Abbas
  • July 4, 2023
  • Biotechnology

Unlocking the Potential: Genetic Engineering and Transgenic Organisms Explained

An organism that contains genes from a different organism An organism that contains genes from a different organism is called a transgenic organism An organism that contains...
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  • Mohamed Abbas
  • July 4, 2023
  • Biotechnology

Assessing the Correctness of Scientific Claims: A Comprehensive Guide to Evaluating Evidence and Methodology

whether something is right or wrong Determining whether something is right or wrong can be complex and depends on various factors, such as personal beliefs, cultural values,...
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  • Mohamed Abbas
  • July 4, 2023
  • Biotechnology

Understanding Gene Therapy for Duchenne Muscular Dystrophy – Potential Treatments and Promising Advances

A genetic disorder that could be treated with gene therapy One example of a genetic disorder that could potentially be treated with gene therapy is Duchenne muscular...
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  • Mohamed Abbas
  • July 4, 2023
  • Biotechnology

Exploring the Potential of Gene Therapy in Treating Genetic Diseases and Disorders

treating diseases or disorders with the insertions of genes Treating diseases or disorders with the insertions of genes is a relatively new field of medicine known as...
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  • Mohamed Abbas
  • July 4, 2023
  • Biotechnology

Genetic Analysis and Genomics: Exploring the Structure, Function, and Variation of Genes

the study of the genes of an organism or species The study of the genes of an organism or species is known as genetic analysis or genomics...
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