Analyzing the Impact of a DNA Substitution on Amino Acid Sequence: A Detailed Examination

DNA sequence (normal) – TAC GTA GTC ACC TAA TGG ATC Amino acid sequence – met his gln trp ile thr stop DNA sequence 2 – TAC GTA GTC AGC TAA TGG ATC amino acid sequence – met his gln ser ile thr stop what is the effect of this substitution on this amino acid sequence?

The given substitution in the DNA sequence results in a change in the corresponding amino acid sequence

The given substitution in the DNA sequence results in a change in the corresponding amino acid sequence. Let’s analyze the effect of this substitution on the amino acid sequence.

The original DNA sequence:

TAC GTA GTC ACC TAA TGG ATC

corresponds to the following amino acid sequence:

Met – His – Gln – Trp – Ile – Thr – Stop

The substituted DNA sequence:

TAC GTA GTC AGC TAA TGG ATC

results in the following amino acid sequence:

Met – His – Gln – Ser – Ile – Thr – Stop

The substitution occurs at the tenth base in the DNA sequence, where an adenine (A) is replaced with a cytosine (C). This change alters the codon TAC, which codes for the amino acid methionine (Met), to TGC, which codes for the amino acid serine (Ser).

Therefore, the effect of this substitution is that instead of the original DNA sequence encoding the amino acid sequence “Met – His – Gln – Trp – Ile – Thr – Stop,” it now encodes the amino acid sequence “Met – His – Gln – Ser – Ile – Thr – Stop.”

More Answers:

Understanding Frameshift Mutations: Causes, Effects, and Implications for Genetic Disorders
Identifying Point Mutation in DNA Sequence and its Impact on Amino Acid Sequence
Exploring a Missense Mutation in DNA Sequence 3: Substitution of Valine (Val) with Cysteine (Cys)

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