Unlocking the Importance of Amino Group: An Insight into its Role in Biological Molecules

Which of the six important chemical groups can act as a base by taking up (essentially removing) a H+ ion from its surrounding water?

Amino, NH2 or N+H3 when “ionized”

The six important chemical groups are hydroxyl group (-OH), carbonyl group (-C=O), carboxyl group (-COOH), amino group (-NH2), sulfhydryl group (-SH), and phosphate group (-PO4). Out of these six chemical groups, the amino group (-NH2) can act as a base by taking up (essentially removing) a H+ ion from its surrounding water. This is because the nitrogen atom in the amino group has a lone pair of electrons that can accept an H+ ion and form a positively charged ammonium ion (NH3+). This property of the amino group makes it an important functional group in many biologically important molecules such as amino acids, proteins, and nucleic acids.

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