Please choose the true statement:a. PKU (phenylketonuria) results from a defect in the synthesis of phenylalanine.b. Gout results from a defect in the salvage pathway of purines.c. Huntington’s disease results from a defect in the purine salvage pathway.d. Lesch-Nyhan syndrome results from a defect in the purine salvage pathway.
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The true statement is b. Gout results from a defect in the salvage pathway of purines.
Gout is a metabolic disorder that results from the accumulation of uric acid crystals in joints and tissues. Uric acid is a waste product of purine metabolism, and gout occurs when there is an overproduction of uric acid or a problem with the body’s ability to excrete it. The salvage pathway of purines refers to the process by which cells recycle purine molecules to create new nucleotides. A defect in this pathway can lead to an excess of uric acid, which can then crystallize and cause gout.
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