From a practical standpoint, would it be advantageous for these potential drugs to be less chemically stable than the substrate?
No, because of shelf life and time to reach target
From a practical standpoint, it would not be advantageous for potential drugs to be less chemically stable than the substrate. This is because drugs are typically administered in controlled doses to achieve a therapeutic effect, and unpredictable stability could result in unpredictable and potentially harmful effects on the patient.
In addition, chemically unstable drugs may undergo degradation or decomposition during manufacturing, packaging, shipping or storage, leading to inconsistent potency and reduced shelf-life. This could result in increased costs due to the need for more frequent manufacturing/batch testing, and potential safety concerns for patients.
Therefore, it is important for potential drugs to be chemically stable to ensure consistent potency, efficacy, safety, and shelf-life, and to minimize the need for further testing and regulatory approval.
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