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  • Mohamed Abbas
  • June 20, 2023
  • Biochemistry

Understanding the Essential Role of Uroporphyrinogen Decarboxylase in Heme Synthesis and its Link to Porphyria

reaction 4 of heme synthesis location: cytosolenzyme: uroporphyrinogen III synthasecyclization of linear tetrapyrrole into uroporphyrinogen III which is an asymmetric ring The fourth reaction in heme synthesis...
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  • Mohamed Abbas
  • June 20, 2023
  • Biochemistry

Understanding the Crucial Role of Reactions 5 and 6 in Heme Synthesis: From PBG to HMB

reactions 5 and 6 of heme synthesis location: mitochondriaform methyl and vinyl side chains and alter saturation of ring constituents, ending with protoporphyrin IX. Heme synthesis is...
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  • Mohamed Abbas
  • June 20, 2023
  • Biochemistry

Heme Synthesis: The Vital Role of Ferrochelatase in Inserting Iron for Essential Protein Function

last reaction of heme synthesis ferrochelatase (enzyme) chelates ferrous iron into protoporphyrin IX to form heme. Occurs in mitochondria The final step in the heme synthesis pathway...
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  • Mohamed Abbas
  • June 20, 2023
  • Biochemistry

The Ins and Outs of Heme Synthesis: A Comprehensive Overview of the Complex Pathway and its Regulation

all steps of heme synthesis -delta aminolevulinate synthase (ALAS) catalyzes condensation reaction between succinyl CoA and glycine to form delta aminolevulinate (ALA), gives of CoA and CO2-porphobilinogen...
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  • Mohamed Abbas
  • June 20, 2023
  • Biochemistry

Understanding Acute Intermittent Porphyria (AIP) and Congenital Erythropoietic Porphyria (CEP): Symptoms and Treatment

problems with heme synthesis pathway. There are two types: acute intermittent and congenital erythropoietic. They are caused by enzyme deficiencies porphyrias Heme synthesis is a complex pathway...
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  • Mohamed Abbas
  • June 20, 2023
  • Biochemistry

Unlocking the Role of Kinases in Biological Processes: A Comprehensive Overview and Therapeutic Implications

Kinase Enzymes that modify protein groups by the transfer of a phosphate group A kinase is an enzyme that phosphorylates proteins and other molecules by transferring phosphate...
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  • Mohamed Abbas
  • June 20, 2023
  • Biochemistry

Unlocking the Power of Transferases: Understanding their Crucial Role in Biological Processes

Transferase Enzymes that catalyze the transfer of functional groups between molecules Transferase is an enzyme that catalyzes the transfer of a chemical group, such as a methyl...
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  • Mohamed Abbas
  • June 20, 2023
  • Biochemistry

Exploring the Role of Decarboxylase Enzymes in Biological Systems

Decarboxylase Enzymes that catalyze the removal of carbon from the carbon chain Decarboxylase is an enzyme that catalyzes the removal of a carboxyl group from an organic...
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