Biochemistry | Senioritis

Mohamed Abbas
June 21, 2023
Biochemistry

Unlocking the Role of Coenzymes in Cellular Metabolism and Essential Enzyme Function

Coenzyme nonprotein organic molecule , frequently a B vitamin , that acts as a cofactor . ( organic cofactor ) A coenzyme is an organic, non-protein molecule...

Mohamed Abbas
June 21, 2023
Biochemistry

Citric Acid Cycle: The Key to Energy Production in Eukaryotic Cells

Citric acid cycle A chemical cycle involving eight steps that completes the metabolic breakdown of glucose molecules to carbon dioxide; occurs within the mitochondrion; the second major...

Mohamed Abbas
June 21, 2023
Biochemistry

Citrate Synthase: The Key Enzyme in the Citric Acid Cycle and its Regulatory Mechanisms

citrate synthase Couples acetyl-CoA to oxaloacetate and then hydrolyzes the resulting product, forming citrate and CoA-SH. This enzyme is regulated by negative feedback from ATP, NADH, succinyl-CoA,...

Mohamed Abbas
June 21, 2023
Biochemistry

The Importance and Role of Aconitase Enzyme in Cellular Metabolism: An Overview

Aconitase isomerizes citrate to isocitrate-dehydration to aconitate and rehydration to isocitrate Aconitase is an enzyme that catalyzes the conversion of citrate to isocitrate in the citric acid...

Mohamed Abbas
June 21, 2023
Biochemistry

Unlocking the Key Role of the Alpha-Ketoglutarate Dehydrogenase Complex (KGDH) in Cellular Energy Metabolism

alpha-ketoglutarate dehydrogenase complex – acts similarly to PDH complex- oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA- generates second CO2 of citric acid cycle-generates second NADH of citric...

Mohamed Abbas
June 21, 2023
Biochemistry

crucial role of Fumarase in Cellular Metabolism and its link to Metabolic Disorders and Cancer

Fumarase Hydration of trans-fumarate to L-malateProduct is stereospecific Fumarase is an enzyme that catalyzes the reversible conversion of fumarate to L-malate in the tricarboxylic acid (TCA) cycle....

Mohamed Abbas
June 21, 2023
Biochemistry

The Crucial Role of Malate Dehydrogenase in Cellular Energy Generation and Glucose Metabolism

malate dehydrogenase -oxidation of malate to oxaloacetate-oxidizing agent is NAD+ Malate dehydrogenase is an enzyme that plays an important role in the citric acid cycle, also known...

Mohamed Abbas
June 21, 2023
Biochemistry

Vital Role of Anaplerotic Reactions in Cellular Metabolism

anaplerotic reactions Reactions that replenish depleted tricarboxylic acid cycle intermediates.-includes pyruvate carboxylase, phosphoenol pyruvate dehydrogenase complex, Malic enzyme and PEP carboxylase Anaplerotic reactions are a group of...