The repetitive steps in fatty acid synthesis are (in order): a. Condensation, Reduction, Thiolysis, Hydrationb. Oxidation, Hydration, Oxidation, Thiolysisc. Reduction, Dehydration, Reduction, Condensation d. Mobilization, Activation, Degradatione. Condensation, Reduction, Dehydration, Reduction
e. Condensation, Reduction, Dehydration, Reduction
The repetitive steps in Fatty Acid Synthesis are:
e. Condensation, Reduction, Dehydration, Reduction
1. Condensation: The first step in fatty acid synthesis is the condensation of two-carbon units, acetyl CoA, to form malonyl-CoA. This reaction is catalyzed by acetyl-CoA carboxylase.
2. Reduction: The next step involves the reduction of the carbonyl group in malonyl-CoA to yield a hydroxyl group. This reaction is catalyzed by NADPH-dependent malonyl-CoA reductase.
3. Dehydration: The next step involves the removal of a water molecule from the hydroxyl group, resulting in the formation of a double bond. This reaction is catalyzed by beta-ketoacyl-ACP synthase.
4. Reduction: The final step involves the reduction of the double bond by NADPH-dependent beta-ketoacyl-ACP reductase, resulting in the formation of a saturated acyl chain. This acyl chain is then transferred to the growing fatty acid chain by the enzyme beta-ketoacyl-ACP synthase.
These four steps are then repeated, with the elongation of the fatty acid chain terminating when the appropriate length of the acyl chain is produced.