Decoding the Role of Consensus Sequence in Prokaryotic Gene Expression: Insights from E. coli

In prokaryotes like E. coli, what does the term consensus sequence refer to?a. It is a DNA sequence that is part of the origin of replication.b. It is a DNA sequence that represents the optimal promoter for transcription.c. It is an RNA sequence that represents the ribosome binding site for the initiation of translation. d. It is an RNA sequence that represents the most common transcription termination site.

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In prokaryotes like E. coli, the term consensus sequence refers to b. It is a DNA sequence that represents the optimal promoter for transcription.

A consensus sequence is a DNA sequence that is present in most (if not all) members of a specific genomic or regulatory element family. The consensus sequence is the average sequence of all the different sequences in the family. In prokaryotes, consensus sequences in the promoter region of a gene are responsible for binding RNA polymerase, initiating transcription, and determining the level of gene expression. The consensus sequence of a promoter region often contains the -10 and -35 regions in E. coli that are recognized by the sigma subunit of RNA polymerase. It is important to note that the consensus sequence of a promoter may differ slightly depending on the type of cell or the type of gene being transcribed.

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