Rapid Removal or Destruction of Neurotransmitter in the Synaptic Cleft: Impact on Postsynaptic Potential Generation

Rapid removal or destruction of neurotransmitter in the synaptic clefta. may affect the ability of the postsynaptic membrane to generate action potentials.b. generates local potentials in the presynaptic terminal.c. is necessary for synaptic transmission.d. may lead to action potentials.e. may stop exocytosis.

may affect the ability of the postsynaptic membrane to generate action potentials.

Option A – Rapid removal or destruction of neurotransmitter in the synaptic cleft may affect the ability of the postsynaptic membrane to generate action potentials. This statement is true. Neurotransmitters are released from the presynaptic terminal into the synaptic cleft and bind to receptors on the postsynaptic membrane. If the neurotransmitter is not rapidly removed or destroyed, it may continue to bind and stimulate the postsynaptic receptor, leading to a continuous depolarization of the postsynaptic membrane and possible desensitization of the receptor. This could affect the ability of the postsynaptic membrane to generate action potentials.

Option B – Rapid removal or destruction of neurotransmitter in the synaptic cleft does not generate local potentials in the presynaptic terminal. This statement is false. Local potentials are generated in the presynaptic terminal due to the opening of voltage-gated calcium channels, which triggers the release of neurotransmitters into the synaptic cleft. Rapid removal or destruction of neurotransmitter in the synaptic cleft does not affect this process.

Option C – Rapid removal or destruction of neurotransmitter in the synaptic cleft is necessary for synaptic transmission. This statement is true. If the neurotransmitter is not rapidly removed or destroyed, it may continue to stimulate the postsynaptic receptor and interfere with the ability of the synapse to transmit information between neurons.

Option D – Rapid removal or destruction of neurotransmitter in the synaptic cleft may lead to action potentials. This statement is false. Action potentials are generated by the movement of ions across the membrane of a neuron. Rapid removal or destruction of neurotransmitter in the synaptic cleft does not directly affect this process.

Option E – Rapid removal or destruction of neurotransmitter in the synaptic cleft may stop exocytosis. This statement is false. Exocytosis is the process by which neurotransmitters are released from the presynaptic terminal into the synaptic cleft. Rapid removal or destruction of neurotransmitter in the synaptic cleft does not directly affect this process.

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