Which one of the following is true?A. Osteoblasts deposit bone matrix around themselves and become osteocytes when they are isolated in lacunae.B. Osteoblasts are large, multinucleated cells that break down calcified bone matrix.C. Osteoclasts deposit bone matrix around themselves and become osteocytes when they are isolated in lacunae.D. Osteoclasts secrete bone matrix and become osteoblasts.
A
The correct answer is A.
Osteoblasts are bone-forming cells and deposit bone matrix around themselves. As osteoblasts deposit bone matrix, they become surrounded and trapped within the matrix and become osteocytes. Osteoblasts are not multinucleated cells, as described in option B.
Option C is incorrect as osteoclasts are bone-resorbing cells and are involved in the breakdown of existing bone matrix, not in the deposition of new bone matrix. Option D is also incorrect as osteoclasts do not secrete bone matrix nor do they become osteoblasts.
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