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  • Mohamed Abbas
  • June 21, 2023
  • Biochemistry

Citrate Synthase: The Key Enzyme in the Citric Acid Cycle and its Regulatory Mechanisms

citrate synthase Couples acetyl-CoA to oxaloacetate and then hydrolyzes the resulting product, forming citrate and CoA-SH. This enzyme is regulated by negative feedback from ATP, NADH, succinyl-CoA,...
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  • Mohamed Abbas
  • June 21, 2023
  • Biochemistry

The Importance and Role of Aconitase Enzyme in Cellular Metabolism: An Overview

Aconitase isomerizes citrate to isocitrate-dehydration to aconitate and rehydration to isocitrate Aconitase is an enzyme that catalyzes the conversion of citrate to isocitrate in the citric acid...
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  • Mohamed Abbas
  • June 21, 2023
  • Biochemistry

Unlocking the Key Role of the Alpha-Ketoglutarate Dehydrogenase Complex (KGDH) in Cellular Energy Metabolism

alpha-ketoglutarate dehydrogenase complex – acts similarly to PDH complex- oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA- generates second CO2 of citric acid cycle-generates second NADH of citric...
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  • Mohamed Abbas
  • June 21, 2023
  • Biochemistry

crucial role of Fumarase in Cellular Metabolism and its link to Metabolic Disorders and Cancer

Fumarase Hydration of trans-fumarate to L-malateProduct is stereospecific Fumarase is an enzyme that catalyzes the reversible conversion of fumarate to L-malate in the tricarboxylic acid (TCA) cycle....
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  • Mohamed Abbas
  • June 21, 2023
  • Biochemistry

The Crucial Role of Malate Dehydrogenase in Cellular Energy Generation and Glucose Metabolism

malate dehydrogenase -oxidation of malate to oxaloacetate-oxidizing agent is NAD+ Malate dehydrogenase is an enzyme that plays an important role in the citric acid cycle, also known...
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  • Mohamed Abbas
  • June 21, 2023
  • Biochemistry

Vital Role of Anaplerotic Reactions in Cellular Metabolism

anaplerotic reactions Reactions that replenish depleted tricarboxylic acid cycle intermediates.-includes pyruvate carboxylase, phosphoenol pyruvate dehydrogenase complex, Malic enzyme and PEP carboxylase Anaplerotic reactions are a group of...
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  • Mohamed Abbas
  • June 21, 2023
  • Anatomy

Viruses: Structure, Replication, Types, Transmission, Prevention, and Treatment

Viruses Small (10-400 nm) acellular entitiesConsist of DNA or RNA enclosed in a protein coat (capsid)Can infect all types of cells: prokaryotic and eukaryotic 1. What are...
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  • Mohamed Abbas
  • June 21, 2023
  • Virology

The Importance of Virions in Virus Replication and Antiviral Therapies: A Comprehensive Overview

Virion A complete viral particle of nucleic acid and protein coat A virion is a complete virus particle that includes the virus genome, capsid or protein coat...
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