Mohamed Abbas, a science teacher at Senioritis.io

Mohamed Abbas
July 4, 2023
Anatomy

The Role of Respiratory Bronchioles and Alveoli in Gas Exchange: A Comprehensive Overview.

respiratory bronchioles and alveoli The respiratory bronchioles and alveoli are two key structures of the respiratory system that play a crucial role in the process of gas...

Mohamed Abbas
July 4, 2023
Pathology

Understanding the Difference Between Liquid Tumors and Solid Tumors in Cancer: A Comprehensive Guide

Liquid tumor; Leukemia: bone marrow; Lyphoma: lymph nodes & tissueSolid tumor: bones & soft tissue A liquid tumor refers to a type of cancer that primarily affects...

Mohamed Abbas
July 4, 2023
Pathology

Detecting the EWS/FLI1 Fusion Transcript in Ewing’s Cancer: A Guide to using Reverse-Transcriptase PCR (RT-PCR) with Targeted Primers

EWS/ EWINGScancer/solid tumort(11:22)Reverse-Transcriptase PCR (RT-PCR)PCR primers designed to yield product only if translocation has occurred In the case of Ewing’s cancer, also known as Ewing’s sarcoma, a...

Mohamed Abbas
July 4, 2023
Pathology

Understanding Abnormal Lymphoblast Production in Bone Marrow

ALLt(9:22)FISH, CISH, RTPCRFound in the bone marrowhigh lymphoblast production leaves little or no normal cell production/population It seems you have provided some information about a specific condition...

Mohamed Abbas
July 4, 2023
Pathology

How Translocation Events Impact Gene Expression: Loss of Function in DNA Binding Proteins

PMLt(15:17)FISH, RTPCRRARA (15) + PML (17) genes both are DNA Binding proteinsWhen translocation = loss of function for both and affects gene expression due to lack of...

Mohamed Abbas
July 4, 2023
Pathology

Exploring the Role of CCND1 Overexpression in Mantle Cell Lymphoma: A Molecular Perspective for Targeted Therapies

MCLt(11:14)FISH, PCR, RTPCRMutations increase expression of CCND1 forcing cells from G1 to S phase. Affects B cells and develops in the mantle zone in the lymph node....

Mohamed Abbas
July 4, 2023
Pathology

Unlocking the Potential: The Significance of the c-myc Gene in Gene Regulation and Cancer Development

BLt(8:14)FISH, CISHc-myc gene codes for transcription factor that controls transcription of other genes The c-myc gene is an important gene that codes for a transcription factor The...

Mohamed Abbas
July 4, 2023
Pathology

A Step-by-Step Guide to Designing Primers for Translocation-Specific PCR: Understanding, Gene Sequences, Breakpoints, Designing Criteria, Validation

RMS/ARMScancer/solid tumort(2:13) or t(1:13)RTPCR, FISHPCR primers designed to yield product only if translocation has occurred To design primers for a translocation-specific PCR (Polymerase Chain Reaction), such as...