Reducing Bacterial Levels in the Gastrointestinal Tract: The Role of Neomycin in Cirrhosis Treatment

Neomycin is prescribed for a client with cirrhosis. What should the nurse explain is the reason for taking this medication?

The nurse should explain to the client with cirrhosis that neomycin is prescribed for its potential to reduce the levels of bacteria in the gastrointestinal tract

The nurse should explain to the client with cirrhosis that neomycin is prescribed for its potential to reduce the levels of bacteria in the gastrointestinal tract. Cirrhosis is a medical condition characterized by scarring and dysfunction of the liver. As the liver becomes damaged, it can no longer perform its normal functions, such as filtering toxins from the blood. Consequently, there is an increased risk of developing infections, particularly in the gastrointestinal tract.

Neomycin is an antibiotic that is commonly used to treat infections caused by bacteria. In the case of cirrhosis, neomycin can be prescribed as a prophylactic or preventative measure to reduce the amount of bacteria in the intestines. This is important because certain bacteria in the gut produce substances called endotoxins, which can be harmful to the liver. By decreasing the bacterial load, neomycin aims to minimize the production and absorption of these endotoxins, potentially reducing the strain on the damaged liver.

It is important to note that neomycin is not absorbed well from the gastrointestinal tract into the bloodstream. This characteristic makes it particularly suited for targeting bacteria within the intestines without causing significant systemic side effects. However, it is necessary to monitor the client’s renal function, as neomycin is excreted by the kidneys. Impaired renal function can lead to increased levels of neomycin in the blood, potentially causing adverse effects.

Furthermore, the nurse should emphasize that neomycin should be taken exactly as prescribed, for the prescribed duration, even if the client’s symptoms improve. It is crucial to complete the full course of treatment to ensure effective bacterial suppression. Additionally, the nurse should inform the client about potential side effects of neomycin, such as diarrhea, nausea, and allergic reactions. If any concerning symptoms arise while taking the medication, the client should promptly report them to their healthcare provider.

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