Dispelling the Myths: Fatty Acids as the Primary Precursor for Ketone Body Synthesis

Which of the following statements about ketone bodies is FALSE? a. They are water solubleb. They are produced in the liverc. Fatty acids cannot be utilized to produce ketone bodiesd. The brain can use ketone bodies for fuel e. They are made from acetyl CoA

c. Fatty acids cannot be utilized to produce ketone bodies

The false statement about ketone bodies is option “c” which states that fatty acids cannot be utilized to produce ketone bodies. This statement is incorrect because fatty acids are actually the primary source of acetyl CoA, which is the precursor molecule for producing ketone bodies in the liver. When there is an excess of fatty acids, as in fasting or a low-carbohydrate diet, the liver converts them into acetyl CoA which is then used in the synthesis of ketone bodies. Therefore, the correct statement is that fatty acids can be utilized to produce ketone bodies.

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