Infective stage of Trypanosoma (cruzi, brucei, gambiense, and rhodelliense)?
Trypomastigote
The infective stages of the four species of Trypanosoma are:
1. Trypanosoma cruzi – The infective stage of T. cruzi is the trypomastigote form that is found in the feces of the reduviid bug, which is the vector of transmission. When the bug bites a human host, it defecates near the bite site, and the trypomastigotes may enter the bloodstream through the bite wound or mucous membranes.
2. Trypanosoma brucei – The infective stage of T. brucei is the metacyclic trypomastigote form that is found in the saliva of the tsetse fly, which is the vector of transmission. When the fly bites a human host, it injects the metacyclic trypomastigotes into the bloodstream.
3. Trypanosoma gambiense – The infective stage of T. gambiense is the bloodstream form that is found in the peripheral blood of infected humans. It can be transmitted to other humans through the bites of infected tsetse flies.
4. Trypanosoma rhodesiense – The infective stage of T. rhodesiense is the bloodstream form that is found in the peripheral blood of infected humans. It can also be transmitted to humans through the bites of infected tsetse flies.
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