Carcinogenesis
Initiation and promotion of cancer; series of molecular changes after exposure to a carcinogen
Carcinogenesis is the process of formation and development of cancer in the body. It involves the transformation of normal cells into cancerous cells that grow and multiply uncontrollably, leading to the formation of tumors and, in some cases, the spread of cancerous cells to other parts of the body.
Carcinogenesis occurs as a result of genetic and environmental factors that damage DNA, the genetic material that controls cell growth and division. These factors include exposure to carcinogens (chemicals, radiation, and viruses), inherited genetic mutations, and lifestyle factors such as tobacco use, poor diet, and lack of exercise.
The process of carcinogenesis involves several stages. The first stage involves the initiation of genetic damage, which may be caused by exposure to carcinogens or inherited genetic mutations. The second stage involves the promotion of mutated cells to proliferate and form pre-cancerous lesions. The third stage involves the progression of pre-cancerous cells to become cancerous, resulting in the formation of tumors. The final stage involves the metastasis of cancerous cells to other parts of the body, which can cause the spread of cancer and increased severity of the disease.
Understanding the mechanisms and risk factors involved in carcinogenesis is crucial for the development of effective cancer prevention and treatment strategies. Early detection of cancer is also important for successful treatment outcomes.
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