2pq
frequency of heterozygous genotype
The term 2pq is commonly used in genetics and refers to the frequency of individuals that are heterozygous for a particular gene in a population.
In Mendelian genetics, genes occur in pairs called alleles, where an individual inherits one allele from each parent. If an individual has two different alleles for a particular gene, they are known as heterozygous.
The frequency of heterozygous individuals in a population can be calculated using the Hardy-Weinberg equation, which states that the frequency of homozygous dominant individuals (p²), homozygous recessive individuals (q²), and heterozygous individuals (2pq) will always add up to 1 in a large, random-mating population.
So, 2pq represents the frequency of heterozygous individuals in a population, where p represents the frequency of the dominant allele and q represents the frequency of the recessive allele.
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