Immune cells of the epidermis tend to be found in the stratum
spinosum
corneum layer of the epidermis. These cells are known as Langerhans cells and they play an important role in the body’s immune defense system. Langerhans cells are dendritic cells that are responsible for detecting and capturing foreign substances that enter the body through the skin.
Once these foreign substances are captured, Langerhans cells migrate to nearby lymph nodes where they activate other immune cells to mount an immune response against the invading pathogen. Langerhans cells also play a role in recognizing and responding to skin cancer cells.
In addition to Langerhans cells, there are other immune cells found in the epidermis such as T cells and natural killer cells. T cells are a type of lymphocyte that plays a critical role in both the innate and adaptive immune response. They recognize and destroy infected or cancerous cells in the skin.
Natural killer cells are lymphocytes that are part of the innate immune system. They are able to recognize and destroy infected or cancerous cells without prior exposure to the pathogen or cancer cell. Natural killer cells are an important part of the immune system’s first line of defense against pathogens.
In summary, immune cells of the epidermis including Langerhans cells, T cells, and natural killer cells are located in the stratum corneum layer of the epidermis. These cells are responsible for identifying and destroying foreign substances, infected cells, and cancerous cells that enter the body through the skin.
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