Optimizing Prenatal Screening: Why Testosterone Levels Are Not Included in the Triple Screen Test

The nurse is caring for a couple who is having a triple screen done. The nurse would least likely expect what level to be tested?A. α-FetoproteinB. Human chorionic gonadotropin C. Unconjugated estriolD. Testosterone

Answer: DRationale: A triple screen tests α-fetoprotein (AFP), human chorionic gonadotropin (hCG), and unconjugated estriol (uE3). Testosterone is not included

D. Testosterone is the least likely level to be tested during a triple screen. The triple screen test is a prenatal screening test that measures the levels of three substances in the blood of a pregnant woman including α-Fetoprotein (AFP), Human chorionic gonadotropin (HCG), and unconjugated estriol (uE3). These substances are used to assess the risk of a birth defect such as Down syndrome, neural tube defects, and other chromosomal abnormalities. Testosterone is not typically measured during the triple screen test because it is not an indicator of fetal abnormalities.

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