Which of the following RPI results will suggest an inadequate response of erythropoiesis by bone marrow in response to anemia?
<2.0
The RPI (reticulocyte production index) is a measure of bone marrow’s response to anemia. An RPI value of less than 2 suggests an inadequate response of erythropoiesis by the bone marrow in response to anemia.
RPI is calculated using the following formula:
RPI = reticulocyte count (%) x patient hematocrit / normal hematocrit
A low RPI indicates that the bone marrow is not producing enough new red blood cells to compensate for the loss due to anemia or other causes. A value below 2 signifies that erythropoiesis is not increasing enough to maintain the levels of red blood cells. This could be due to several factors, including bone marrow suppression, nutrient deficiencies, or underlying medical conditions.
Therefore, an RPI value of less than 2 would suggest an inadequate response of erythropoiesis by bone marrow in response to anemia.
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