Transcription of (-)ssRNA by RdRP: Critical Step in RNA Virus Life Cycle

(-)ssRNA is transcribed into (+)ssRNA using what?

RNA polymerase encoded by the virus

(-)ssRNA (negative sense single-stranded RNA) molecules are transcribed into (+)ssRNA (positive sense single-stranded RNA) molecules by the enzyme RNA-dependent RNA polymerase (RdRP). RdRP is an RNA polymerase that catalyzes the synthesis of RNA molecules using a RNA template. This enzyme can recognize the (-)ssRNA molecule and use it as a template to synthesize a complementary (+)ssRNA molecule. This process is known as transcription or replication and is a critical step in the life cycle of RNA viruses, such as influenza virus and hepatitis C virus, which have a (-)ssRNA genome. By transcribing their (-)ssRNA genome into (+)ssRNA molecules, these viruses can then use the host cell machinery to create new viral particles and continue their infection cycle.

More Answers:

The History of the First Vaccine: How Edward Jenner Eradicated Smallpox
Cost-effective Strategies for Disease Control: Prevention, Vaccination, and Early Detection
Viruses: Their Composition, Replication, and Impact on Health and the Environment

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