Acute Phase Reactants: Their Role in Immune and Inflammatory Responses and Diagnostic Significance.

Acute phase reactants

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Acute phase reactants are proteins that are synthesized by the liver in response to inflammatory cytokines in the body. These proteins play an important role in the body’s immune and inflammatory response to injury or infection.

Some examples of acute phase reactants are:

1. C-reactive protein (CRP) – a protein that is produced by the liver in response to inflammation and is used as a marker of inflammation in the body.

2. Serum amyloid A (SAA) – a protein that is produced by the liver in response to inflammation and is involved in tissue repair and remodeling.

3. Ferritin – an iron storage protein that is produced by the liver in response to inflammation.

4. Fibrinogen – a protein that is involved in blood clotting and is produced by the liver in response to inflammation.

5. Haptoglobin – a protein that binds to hemoglobin and is produced by the liver in response to inflammation.

The levels of these acute phase reactants in the blood can be measured by various laboratory tests and can help diagnose and monitor various inflammatory and infectious diseases. Additionally, monitoring these levels can also help in assessing the effectiveness of treatment and response to therapy.

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Cytokines: Vital Signalling Proteins Regulating Immune Response and Physiological Processes.

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